Enhanced molecular transport within subregions of the nasal cavity - BC-1000
Genre de projet: RechercheDiscipline(s) souhaitée(s): Biochimie / biologie moléculaire, Sciences de la vie, Chimie, Sciences naturelles, Physique et astronomie
Entreprise: Rocket Science Health Corp.
Durée du projet: 6 mois à 1 an
Date souhaitée de début: Dès que possible
Langue exigée: Anglais
Emplacement(s): Victoria, BC, Canada
Nombre de postes: 1
Niveau de scolarité désiré: Maîtrise
Ouvert aux candidatures de personnes inscrites à un établissement à l’extérieur du Canada: No
Au sujet de l’entreprise:
Rocket Science Health develops precision drug delivery technologies focused on brain-targeted therapeutics and vaccines. Our needle-free intranasal device enables non-clinical self-administration for at-home care, emergency rescue, and mass immunization. Its fluidics are specifically engineered for today's delicate biologics and dose-dependent drugs.
Veuillez décrire le projet.:
Rocket Science Health (RSH) develops cutting edge intranasal devices, and as part of our research program we are seeking a deeper understanding of molecular transport through mucus layers for a variety of liquid formulations. The project will include a study of diffusion rates in relevant synthetic media for hydrogels and polymer fluids. The effects of surfactants will also be studied. The RSH team will provide engineering support for test rigs and analytical support for analysis of results. The goal is to optimize transport mechanics for RSH's family of devices. The project should build a strong research collaboration with the local scientific community with a large potential for commercialization.
Expertise ou compétences exigées:
The ideal candidate is a master's or doctoral-level student with strong communication skills, solid fundamentals in micro-fluidics experiments, and an aptitude for experimental design. Preparation and handling of hydrogels, polymer fluids, and synthetic mucus solutions is required. Experience estimating diffusion coefficients, permeability, wetting angles, and surface tension from lab measurements is a key skill. Competence with various forms of microscopy is required. Image processing/analysis skills in Python is a big plus.
